Activity of Investigational Polymyxin-B-Like Compound (SPR206) against Set of Enterobacteriaceae Organisms Responsible for Human Infections Posted on June 24, 2019 at 3:19 pm.Written by Spero Therapeutics View Presentation Post navigation Optimisation of Next-Generation Polymyxins Leading to SPR206 as a Development CandidateSafety, Tolerability, Pharmacokinetics, and Drug Interaction Potential of SPR741, An Intravenous Potentiator, After Single and Multiple Ascending Doses and When Combined with Beta-Lactam Antibiotics in Healthy Subjects