Tebipenem, the First Oral Carbapenem Antibiotic Posted on July 27, 2018 at 2:47 pm.Written by Spero Therapeutics Expert Review of Anti-infective Therapy, DOI: 10.1080/14787210.2018.1496821 Michael J. Pucci, Akash Jain, Luke Utley, Thomas Zabawa & Thomas R. Parr View Presentation Post navigation Assessment of the In Vivo Activity of SPR741 in Combination with Azithromycin against Multidrug Resistant Enterobacteriaceae isolates in the Neutropenic Murine Thigh Infection modelCharacterization of SPR994, an Orally Available Carbapenem, with Activity Comparable to Intravenously Administered Carbapenems