Hope for Patients with Rare and Infectious Diseases

Spero Therapeutics is committed to advancing new therapies for patients with rare diseases and multidrug-resistant (MDR) bacterial infections.

Spero Therapeutics’ pipeline targets areas with high unmet medical needs, addressing therapeutic areas where approved therapies are scarce or where the prevailing standard of care may be suboptimal.

A closeup of a couple holding hands
a doctor with an elderly woman patient

Our Mission

Spero Therapeutics is dedicated to delivering differentiated medicines to help patients suffering from rare diseases and multidrug-resistant (MDR) bacterial infections.

Tebipenem HBr

An investigational oral carbapenem being developed for the treatment of complicated urinary tract infection (cUTI) and acute pyelonephritis (AP)

Tebipenem HBr (tebipenem pivoxil hydrobromide) is an investigational oral carbapenem being developed for the treatment of cUTI and AP to potentially help patients avoid hospitalizations and/or reduce the duration of in-patient therapy. If approved, Tebipenem is positioned to be the first oral carbapenem for this condition.

SPR206

An investigational intravenous (IV) product candidate for treating MDR gram-negative infections

SPR206 is an investigational IV direct-acting antibiotic being developed against gram-negative bacterial infections in participants with hospital-acquired or ventilator-associated bacterial pneumonia. SPR206 has shown activity against MDR gram-negative pathogens, including carbapenem-resistant ones, in preclinical studies. An Investigational New Drug application has been cleared by the FDA to advance SPR206 into a Phase 2 clinical trial.

Learn More About SPR206
Learn more about SPR206

Partnerships

Spero Therapeutics believes that forming collaborations with external partners is essential to maximizing the reach and impact of our innovative therapies for patients.

Investor Relations

Stock information, SEC filings, corporate governance, IR resources and more.

Careers

Join our life-changing mission to deliver differentiated treatments for those affected by rare and MDR bacterial infections. We seek individuals with unique talents who share our passion.